Molecular forms of butyrylcholinesterase and obesity
نویسندگان
چکیده
منابع مشابه
Molecular forms of butyrylcholinesterase and obesity
This study compared obese (N = 134) and unobese (N = 92) male blood donors, regarding the relative intensity (RI) and activity of different molecular forms (G1, G2, G4 and G1-ALB) of butyrylcholinesterase (BChE, EC 3.1.1.8) found in plasma, thereby searching for an association between these variables with obesity and SNPs of exons 1 and 4 of the BCHE gene. It was shown that obese and unobese in...
متن کاملHuman butyrylcholinesterase polymorphism: Molecular modeling.
BACKGROUND Prolonged apnoea following injection of ester-containing myoralaxants was first described in 1953. Because a large part of administered succinylcholine is shortly hydrolyzed by plasma butyrylcholinesterase (BChE) under normal conditions, prolonged apnoea was attributed to deficiency in BChE. It was found that BChE deficiency was due to genetic variations. Human BChE gene shows a larg...
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OBJECTIVE To describe novel C-reactive protein (CRP) molecular forms (mf) in human plasma. DESIGN AND METHODS Five novel CRP-mfs, disctinct from the previously described native (nCRP) and modified (mCRP) C-reactive proteins, were separated from human plasma by polyacrylamide gel electrophoresis and immunodetected by western blot in subjects with or without increased BMI, cardiovascular diseas...
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Butyrylcholinesterase is an enzyme with few known physiological functions. It is related to acetylcholine that was shown to be expressed in a variety of life forms. We performed a search using the human butyrylcholinesterase gene (HGNC:983;MIM:177400), and found the sequence in a broad spectrum including plants, bacteria and animals. Therefore butyrylcholinesterase appears to have evolved early...
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ژورنال
عنوان ژورنال: Genetics and Molecular Biology
سال: 2010
ISSN: 1678-4685,1415-4757
DOI: 10.1590/s1415-47572010005000072